Alfonso™ validation whitepapers
ASTM F2077 axial compression of spinal fusion devices
Validation of our ASTM F2077 axial compression model for titanium spinal interbody fusion devices in Alfonso™
ASTM F1839-08-2021 solid rigid polyurethane foam models
Validation of our 10,15,20, and 40 PCF solid rigid polyurethane foam material models in Alfonso™
ASTM F543-A3 orthopaedic screw pull-out from PU foam
Validation of our ASTM F543-A3 orthopaedic screw pull-out from PU foam models in Alfonso™
ASTM F1264 four-point bending of intramedullary nails
Validation of our ASTM F1264 four-point bending of intramedullary nails in Alfonso™
ASTM F2267 subsidence of spinal fusion devices
Validation of our ASTM F2267 subsidence model for titanium spinal interbody fusion devices in Alfonso™
Peer-reviewed journal articles and conference abstracts
Paper Presentation at the 2021 OTA Annual Meeting
Kulper, S. A., Lin, T.H, Ren, X., Coombs, D. J., Bushelow, M., Fang, E., Alvi, A. A., Ueda, E. A., Zhang, T., Fang, C. X.
Lifespans, Ltd., The University of Hong Kong, Tongji University, DePuy Synthes, Queen Mary Hospital
A novel mesh-free method for accurately simulating the crushing and cracking behavior of trabecular bone tissue with a wide range of clinically relevant bone mineral density values.
Lifespans Soft Bone Simulator Validation Article
Kulper, S. A., Fang, C. X., Ren, X., Guo, M., Sze, K. Y., Leung, F. K., & Lu, W. W. (2018).
Development and initial validation of a novel smoothed particle hydrodynamics based simulation model of trabecular bone penetration by metallic implants.
Journal of Orthopaedic Research®, 36(4), 1114-1123.
https://doi.org/10.1002/jor.23734
[pub]
Lifespans Soft Tip Mechanical Theory Article
Kulper, S.A., Sze, K.Y., Fang, C.X., Ren, X., Guo, M., Schneider, K., Leung, F., Lu, W. and Ngan, A. (2018).
A novel fracture mechanics model explaining the axial penetration of bone-like porous, compressible solids by various orthopaedic implant tips.
Journal of the Mechanical Behavior of Biomedical Materials, 80, 128-136. https://doi.org/10.1016/j.jmbbm.2018.01.025
Paper Presentation at the 2023 ISTA Annual meeting
Janice Oentaryo, PhD; Rezaul Tharim; Sloan Kulper, PhD; Erica Ueda Boles, PhD
Lifespans, Ltd.,
The University of Hong Kong
Computational models of ASTM F543-17 A3 (screw pull-out) were generated using the particle-based simulation system Alfonso and its predictions were compared to physical experimental test results.
Paper Presentation at the 2024 Orthopedic Research Society
Janice Oentaryo, PhD; Rezaul Tharim; Sloan Kulper, PhD; Erica Ueda Boles, PhD
Lifespans, Ltd.,
The University of Hong Kong
The novel mesh-free computational modeling system in the present study can accurately predict the maximum pull-out loads of several typical orthopedic screws in two common PU foam grades per ASTM F543-17 A3.
Paper Presentation at the 2024 NASS Annual meeting
Janice Oentaryo, PhD; Rezaul Tharim; Sloan Kulper, PhD; Erica Ueda Boles, PhD
Lifespans, Ltd.,
The University of Hong Kong
Simulated models of ASTM F2077 compression of 3D-printed spinal spacers, using microCT-based imaging at ultra high-resolution for input of implant geometry.
Intellectual Property
Alfonso™ embodies and utilizes proprietary processes, algorithms, and models of implants, bone and bonelike materials for simulation. It is based on intellectual property rights exclusive to Lifespans Limited - including proprietary copyright software and know-how - and has pending patent rights. Any non-exclusive technologies utilized by this system are open-source and/or are properly licensed for commercial use. No other third party proprietary software or simulation solvers, such as those of Abaqus, Ansys, Mimics, etc., are utilized in or by the Alfonso simulator.
Learn more about us
Click the link below to read about our business, technical, and clinical team members.